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SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status.
Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2313137120. doi: 10.1073/pnas.2313137120. Epub 2023 Nov 16.
Proc Natl Acad Sci U S A. 2023.
PMID: 37972068
Free PMC article.
KSR1 regulates small-cell lung carcinoma tumor initiation and therapy resistance.
Chatterjee D, Svoboda RA, Huisman DH, Vieira HM, Rao C, Askew JW, Fisher KW, Lewis RE.
Chatterjee D, et al. Among authors: askew jw.
bioRxiv [Preprint]. 2024 Apr 11:2024.02.23.581815. doi: 10.1101/2024.02.23.581815.
bioRxiv. 2024.
PMID: 38464216
Free PMC article.
Preprint.
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Searching for evidence of DFNB2.
Astuto LM, Kelley PM, Askew JW, Weston MD, Smith RJ, Alswaid AF, Al-Rakaf M, Kimberling WJ.
Astuto LM, et al. Among authors: askew jw.
Am J Med Genet. 2002 May 15;109(4):291-7. doi: 10.1002/ajmg.10384.
Am J Med Genet. 2002.
PMID: 11992483
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Splice-altering variant in COL11A1 as a cause of nonsyndromic hearing loss DFNA37.
Booth KT, Askew JW, Talebizadeh Z, Huygen PLM, Eudy J, Kenyon J, Hoover D, Hildebrand MS, Smith KR, Bahlo M, Kimberling WJ, Smith RJH, Azaiez H, Smith SD.
Booth KT, et al. Among authors: askew jw.
Genet Med. 2019 Apr;21(4):948-954. doi: 10.1038/s41436-018-0285-0. Epub 2018 Sep 24.
Genet Med. 2019.
PMID: 30245514
Free PMC article.
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